AffinityDNA DNA Test for Caffeine Metabolism | CYP1A2 Gene | at Home Cheek Swab Sample Collection Kit | Results in 7-10 Working Days | No Extra Fees

Description

• ACCURATE DNA TEST: The genetic analysis examines the CYP1A2 gene. The test evaluates the speed of metabolisation of caffeine and identifies risk of side effects such as nausea, tachycardia, insomnia and hypertension. Accurate results.
• PERSONALISED DNA TEST REPORT: Knowing your genetic information is very useful. With your DNA test kit you can adapt your fitness habits and diet to improve your well-being.
• MAKE MORE INFORMED DECISIONS: The recommendations provided by the DNA Test For Caffeine Metabolism are tailored specifically to your body.
• COMPLETE TESTING KIT: The DNA Sample Collection Kit contains 2 x sterile mouth swabs (both for 1 person), step-by-step sample collection instructions, registration form & return envelope. Results in 7-10 working days from receipt of your sample at the laboratory.
• PREMIUM SPORTS DNA TEST PACAKGE: Please see options above for a discounted package containing all 5 Sports DNA tests: Athletic Aptitude: Power or Resistance; Athletic Recovery Antioxidant Capacity; Athletic Recovery Anti-Inflammatory; Joint Resistance and Caffeine Metabolism.

The Caffeine Metabolism DNA test evaluates the speed of metabolisation of caffeine. Poor metabolisers should limit or eliminate caffeine intake as they have a greater susceptibility to hypertension.
Genetic analysis examines the CYP1A2 gene which encodes the cytochrome P450 protein CYP1A2 which, at the liver level, is the primary enzyme involved in metabolism of caffeine.
Caffeine has its primary biological effects at the central nervous system level by acting as an antagonist to adenosine (by binding to A2A adenosine receptors) which causes changes in dopaminergic conduction and variations in the expression of some genes that lead to the known effects on the brain and behaviour.
The unfavourable variant of the gene for the enzyme causes slow metabolisation of caffeine, which prolongs its effects and can increase the risk of developing hypertension. In particular, a variable gene site is evaluated: GST008, an index of the body's ability to metabolise caffeine, because it influences the functionality of a key enzyme in this metabolism: cytochrome P450 CYP1A2. Carriers of one or both unfavourable variants are subject to a greater need to control and reduce their daily caffeine intake. The unfavourable variant is A.
The unfavourable allelic variant predicts a greater risk for its carriers compared to the general population to suffer from hypertension as they are slow metabolisers of caffeine.
The indication of susceptibility is based on scientific evidence that associates the unfavourable allelic variants detected by the analysis with an increase in the subject's susceptibility compared to the general population. This increase in susceptibility is a probabilistic measure because it does not take into account the subject's lifestyle but only his own genetic makeup.
Therefore, it is not a diagnosis, and therefore does not imply a cause-effect relationship.
Results are accurate and available within 10-15 working days from receipt at the laboratory.

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